Breast Milk Antibody Promotes a Healthy Gut into Adulthood
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چکیده
This month’s issue features articles about antioxidants in dairy foods reducing inflammation in macular degeneration, the breakdown of human milk proteins in the infant stomach to produce peptides with potential biofunctions, the presence of beta-casomorphins in colostrum and breastmilk that affect serotonin receptors, and clinical studies showing a potential relationship between milk fat globules and cognitive development. Enjoy!
منابع مشابه
Secretory antibodies in breast milk promote long-term intestinal homeostasis by regulating the gut microbiota and host gene expression.
Maintenance of intestinal homeostasis requires a healthy relationship between the commensal gut microbiota and the host immune system. Breast milk supplies the first source of antigen-specific immune protection in the gastrointestinal tract of suckling mammals, in the form of secretory IgA (SIgA). SIgA is transported across glandular and mucosal epithelial cells into external secretions by the ...
متن کاملLessons from mother: Long-term impact of antibodies in breast milk on the gut microbiota and intestinal immune system of breastfed offspring
From birth to adulthood, the gut microbiota matures from a simple community dominated by a few major bacterial groups into a highly diverse ecosystem that provides both benefits and challenges to the host. Currently there is great interest in identifying environmental and host factors that shape the development of our gut microbiota. Breast milk is a rich source of maternal antibodies, which pr...
متن کاملAutoantibodies to αS1-Casein Are Induced by Breast-Feeding
BACKGROUND The generation of antibodies is impaired in newborns due to an immature immune system and reduced exposure to pathogens due to maternally derived antibodies and placental functions. During nursing, the immune system of newborns is challenged with multiple milk-derived proteins. Amongst them, caseins are the main constituent. In particular, human αS1-casein (CSN1S1) was recently shown...
متن کاملAssessment of bacterial diversity in breast milk using culture-dependent and culture-independent approaches.
Initial neonatal gut colonisation is a crucial stage for developing a healthy physiology, beneficially influenced by breast-feeding. Breast milk has been shown not only to provide nutrients and bioactive/immunological compounds, but also commensal bacteria, including gut-associated anaerobic Bifidobacterium spp. The aim of the present study was to investigate bacterial diversity in breast milk,...
متن کاملEarly infant feeding and adiposity risk: from infancy to adulthood.
INTRODUCTION Systematic reviews suggest that a longer duration of breast-feeding is associated with a reduction in the risk of later overweight and obesity. Most studies examining breast-feeding in relation to adiposity have not used longitudinal analysis. In our study, we aimed to examine early infant feeding and adiposity risk in a longitudinal cohort from birth to young adulthood using new a...
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